[Comparative study of the effect of hippophae and sunflower oil on patients with coronary arteriosclerosis]. [Therapeutic endoscopy in combined therapy of gastroduodenal ulcers]. View abstract. J Nutr.Biochem. Additionally, the expression of apoptotic and antiapoptotic proteins was decreased and increased, respectively, with administration of sea buckthorn seed PACs.Wang 2016 The antioxidant and potential protective effect of wild sea buckthorn leaf extract (aqueous) against cataracts was demonstrated using goat lenses. View abstract. Medically reviewed by Drugs.com. Common cold. View abstract. 2012;19(3):153-6. Wang MH, Zhu F Lu M et al. Anti-inflammatory– The oil reduces inflammation both when used topically and when used internally. Information regarding safety and efficacy during pregnancy and lactation is lacking. This delaying effect was expected, as sea buckthorn is naturally lipid rich; the overall triacylglycerol response did not change.Linderborg 2012, In a study of 88 patients, total flavones in sea buckthorn did not alter the sympathetic activity in treatment of hypertension when compared with patients treated with nifedipine and extended-release verapamil.Zhang 2001. It is a spiny deciduous shrub. Farmakol Toksikol. View abstract. In natural medicine, there are many uses and indications for the Sea Buckthorn. View abstract. Hell J Nucl Med. The common glycosides found in berries include those of quercetin, kaempferol, and myricetin, whereas the most abundant aglycon is isorhamnetin.Zheng 2016 The flavonol glycosides, sugars, and organic acids are preserved best in extracts and are present in comparable amounts to those in dried whole berries when the supercritical carbon dioxide extraction method without further ethanol extraction is used. Fruit and berry extracts from sea buckthorn inhibited the growth of colon cancer cells HT29 and breast cancer cells MCF-7 in a dose-dependent manner. Additionally, effects on insulin, fasting blood glucose, and lipid parameters were measured. After 12 weeks, 350 mg twice daily of sea buckthorn supplementation added to standard therapy provided no statistically significant benefit compared with standard therapy alone for edema, anorexia, weakness, oliguria, blood pressure, hemoglobin, serum creatinine, phosphorus, blood urea, or weight. Patients took 5 g (as 10 capsules) of sea buckthorn seed or pulp oil, or paraffin oil (control group) orally daily for 4 months.Yang 1999 After 1 month of treatment, patients receiving the seed oil reported improvement of atopic dermatitis symptoms, which correlated to an increase in alphalinolenic acid in plasma lipids. Phytother.Res. Early research suggests that taking sea buckthorn by mouth for up to 8 months might reduce high blood pressure similarly to certain blood pressure-lowering drugs. Sea buckthorn arrived through golf course landscapers who planted it to stabilise the dunes and provide a wind break. Sea buckthorn might slow blood clotting. Singh RG, Singh P, Singh PK, et al. View abstract. It also has beneficial effects on skin and mucosa. When rendered as a juice or oil, sea buckthorn benefits the body in many ways. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . The harvested fruit is quite acidic and its juices are often combined with those of sweeter fruits, such as grape or pear, to make it more palatable. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Ananas de Sibérie, Argasse, Argousier, Argousier Faux-Nerprun, Bourdaine Marine, Buckthorn, Chharma, Dhar-Bu, Épine Luisante, Épine Marrante, Espino Armarillo, Espino Falso, Faux Nerprun, Finbar, Grisset, Hippophae rhamnoides, Meerdorn, Oblepikha, Olivier de Sibérie, Purging Thorn, Rokitnik, Sallow Thorn, Sanddorn, Saule Épineux, Sea Buckhorn, Sceitbezien, Sea-Buckthorn, Seedorn, Star-Bu, Tindved, White Sea Buckthorn. Other Traditional Uses and benefits of Sea buckthorn 2000;11(6):338-340. 2009;12(1):55-58. 2008;15(10):793-799. Sterols are found in 1% to 2% of the seed oil and 1% to 3% in the soft parts of the fruit as sitosterol, isofucosterol, campsterol, stigmastanol, citrostadienol, avenasterol, cycloartenol, 24-methylenecycloartanol, and obtusifoliol.Guliyev 2004, Yang 2002, Cakir 2004. View abstract. Compared with controls, inflammatory biomarkers (ie, TNF-alpha, IL-6, vascular endothelial growth factor) were observed to be significantly reduced after sea buckthorn/St. 1986;(9):75. 2014;7:139-44. This article will tell you more about the benefits and uses of sea buckthorn oil. This information should not be used to decide whether or not to take this product. 1987;15(2):97-99. The mechanism of action remains unclear but may involve suppression of arachidonic acid synthesis by collagen receptor stimulation.Cheng 2003, The effects of sea buckthorn berry oil on cardiovascular disease risk were studied over a 4-week period in 12 healthy, normolipidemic men in a double-blind, randomized, crossover study. S. aureus grew 1.5 times more in 10% sea buckthorn juice compared with the control. Agrawala, P. K. and Adhikari, J. S. Modulation of radiation-induced cytotoxicity in U 87 cells by RH-3 (a preparation of Hippophae rhamnoides). View abstract. The berries have been used for more than 2,000 years as a medicine and food additive in Europe, Russia, and Asia.Singh 2013, Because of their hemostatic and anti-inflammatory effects, the fruits are added to prescriptions in Indian and Tibetan medicine to treat pulmonary, GI, cardiac (eg, ischemic heart disease), blood, hepatic, and metabolic disorders. Larmo PS, Yang B, Hyssälä J, et al. Seven, B., Varoglu, E., Aktas, O., Sahin, A., Gumustekin, K., Dane, S., and Suleyman, H. Hippophae rhamnoides L. and dexpanthenol-bepanthene on blood flow after experimental skin burns in rats using 133Xe clearance technique. Eczema (atopic dermatitis). Clin.Hemorheol.Microcirc. Renal disease: 350 mg of extract twice daily for 12 weeks; or 2 g/day of oil extract for 8 weeks. 2001;21(3):215. Medicina (Kaunas.) 2004;40(8):753-757. 2013;16(1):38-43. Sea buckthorn is a medium-sized, hardy, deciduous shrub that can grow between 2 and 6 m in height. Nutr.Cancer 2005;51(1):59-67. These extracts inhibited carcinogen-induced forestomach and skin tumorigenesis in mice; mechanisms of action may involve upregulation of phase 2 (eg, glutathione S-dimutase, catalase, glutathione peroxidase, glutathione reductase) and antioxidant enzymes.Hibasami 2005, Sun 2003, Olsson 2004, Padmavathi 2005, Zhang 2005, A leaf extract of sea buckthorn inhibited proliferation of C6 rat glioma cells, possibly through a mechanism of early apoptosis; reduction of reactive oxygen species was noted as well.Kim 2017, Sea buckthorn oil may stimulate the recovery of hematopoiesis after chemotherapy. Hypercarotenemia resulted in excess carotene being stored in the skin; it is also stored in fat. Eur J Clin Nutr 2011;65(3):394-401. Ianev E, Radev S, Balutsov M, et al. Subjective assessments of night sweats were reported by participants in daily logbooks and were significantly less in the treatment group during month 3.Larmo 2014, Uremia is associated with oxidative stress and cellular inflammation. Flavonols from sea buckthorn inhibited promyelocytic leukemia HL-60 cells. Guo X-F, Yang B, Cai W, Li D. Effect of sea buckthorn (Hippophae rhamnoides L.) on blood lipid profiles: A systematic review and meta-analysis from 11 independent randomized controlled trials. Neuroprotection was observed in a dose-dependent manner, with the most effective neuroprotection seen at 100 mcg/mL. Olas B, Kontek B, Szczesna M, et al. View abstract. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Changshun L, Xinming C, Fenrong W, et al. Khirurgiia (Sofiia) 1995;48:30-3. … Am J Clin Nutr. People also use sea buckthorn as a sunscreen or cosmetic, and for a variety of skin problems such as: Radiation damage. J Nutr.Biochem. Uses of Sea Buckthorn Oil. In the liver, the oil from the berries inhibited the Fenton reaction and radiation-mediated generation of hydroxyl radicals, and inhibited superoxide anion–mediated nitroblue tetrazolium reduction and ferrous sulfate–mediated lipid peroxidation. Geetha, S., Sai, Ram M., Singh, V., Ilavazhagan, G., and Sawhney, R. C. Anti-oxidant and immunomodulatory properties of seabuckthorn (Hippophae rhamnoides)--an in vitro study. Sea buckthorn fruit are used to make pies, jams, lotions, teas, fruit wines, and liquors. Thus relieves ulcres and throat irritation. Subsequently, regular estrous cycles were observed only in animals in the intervention and reference groups. 2001:32(4):547. Inhibition of blood platelet adhesion by phenolics rich fraction of Hippophae rhamnoides L. fruits. China New Drug and Clinic 2004;23(8):501-503. Eur.J.Clin.Nutr. 2003;87(2-3):247-251. Whole-body radioprotective effects of SBL-1: a preparation from leaves of Hippophae rhamnoides. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Each leaf is elongate-oblanceolate or elongate-spatulate, green at the top, and silver-ash green on the underside. View abstract. 1970;44(6):69-72. 2001;1(12):903-904. This information may not fit your specific health circumstances. Patients treated with sea buckthorn extract had reduced serum levels of laminin, hyaluronic acid, total bile acid, and collagen types III and IV. View abstract. The primary constituents of the volatile fruit aromas are ethyl dodecenoate, ethyl octanoate, decanol, ethyl decanoate, and ethyl dodecanoate. CONDITIONS OF USE AND IMPORTANT INFORMATION: Patients treated with the pulp oil had increased levels of palmitoleic acid (P<0.05) in plasma phospholipids and neutral lipids; however, these changes did not correlate with symptom improvement. It is also used to treat skin diseases. Early research shows that taking sea buckthorn oil daily for 8 weeks does not help remove waste products from the blood or prevent dry mouth in people undergoing dialysis. The plant is used in the food and cosmetics industries, in traditional medicine, as animal fodder, in horticulture, and for ecological purposes. Indian J.Med.Res. J Nutr 2010;140:1462-8. Life Sci. Chemical and nutritional constituents of sea buckthorn. Chung Kuo Chung Yao Tsa Chih 1994;19:367-70, 384. Backhouse, N., Rosales, L., Apablaza, C., Goity, L., Erazo, S., Negrete, R., Theodoluz, C., Rodriguez, J., and Delporte, C. Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. Maturitas. Zhu F, Hu CY Huang P et al. Xing, J., Yang, B., Dong, Y., Wang, B., Wang, J., and Kallio, H. P. Effects of sea buckthorn (Hippophae rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats. Beaconsfield, UK: Beaconsfield Publishers Ltd, 1998. 2009;41(1):17-26. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. 3. You should talk with your health care provider for complete information about the risks and benefits of using this product. Vestn.Dermatol Venerol. Journal of Herbs, Spices & Medicinal Plants 2009;15(2):203-15. 2008;95(4):383-393. Klin Med (Mosk) 1991;69(7):38-42. Cochrane.Database.Syst.Rev. View abstract. [Effect of flavonoids from the seed and fruit residue of Hippophae rhamnoides L. on glycometabolism in mice]. 8. Early research shows that taking sea buckthorn pulp oil by mouth for 4 months improves atopic dermatitis. It helps to reduce the risk of heart problems. What factors influenced or will influence your purchase? All 3 fiber-rich sea buckthorn preparations, which varied in polyphenol content, delayed lipemia compared with the fiber- and polyphenol-depleted control. 4. Fitoterapia 2007;78(7-8):590-592. It also is found in Canada and the United States.Yang 2001, Sea buckthorn has a rich history of use in treating numerous medical conditions. View abstract. But sea buckthorn doesn't appear to improve the rate at which food empties from the stomach into the intestines. (check all that apply), What factors are most important to you? Clin Interv Aging. However, sea buckthorn seed oil taken by mouth does not have this effect. View abstract. 2007;16 Suppl 1:234-238. Linderborg, K. M., Lehtonen, H. M., Jarvinen, R., Viitanen, M., and Kallio, H. The fibres and polyphenols in sea buckthorn (Hippophae rhamnoides) extraction residues delay postprandial lipemia. Obesity. Chung Hua Yu Fang I Hsueh Tsa Chih 1992;26:227-9. Thumm, E. J., Stoss, M., Bayerl, C., and Schurholz, T. H. Randomized trial to study efficacy of a 20% and 10% Hippophae rhamnoides containing creme used by patients with mild to intermediate atopic dermatitis. J Ren Nutr. Ancient Tibetan medical literature documents the use of sea buckthorn for fever, inflammation, toxicity, abscesses, cough, colds, clearing sputum, laxative purposes, tumors (particularly in the stomach and esophagus), and gynecological diseases.Guliyev 2004, Goel 2002 The flowers are used as a skin softener in Tajikistan.Guliyev 2004 In Mongolia, extracts from the leaves and branches of the plant are used medicinally to treat colitis and enterocolitis in humans and animals. Sea buckthorn decreases and delays insulin response and improves glycaemic profile following a sucrose-containing berry meal: a randomised, controlled, crossover study of Danish sea buckthorn and strawberries in overweight and obese male subjects. Effects of sea buckthorn and bilberry on serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized crossover trial. Sea buckthorn is already being studied for the possibility of suppressing COVID-19, since it contains lactobacilli that suppress purines necessary for the development of coronavirus, as well as succinic and malic acid, which are antiviral agents. Benherlal, P. S. and Arumughan, C. Studies on modulation of DNA integrity in Fenton's system by phytochemicals. Uses, Benefits, Cures, Side Effects, Nutrients in Sea Buckthorn. The different uses of sea buckthorn oil Padmavathi, B., Upreti, M., Singh, V., Rao, A. R., Singh, R. P., and Rath, P. C. Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor. View abstract. Sea buckthorn leaves and flowers are used for treating arthritis, gastrointestinal ulcers, gout, and skin rashes caused by infectious diseases such as measles. Grad, S. C., Muresan, I., and Dumitrascu, D. L. Generalized yellow skin caused by high intake of sea buckthorn. 2005;20(2):247-248. Journal of Pharmacy and Pharmacology (England) 2005;57:1065-1072. View abstract. Nahrung 1999;43(4):228-232. Liver disease: 15 g 3 times daily of sea buckthorn extract for 6 months. It has recently experienced a resurgence in use by people seeking natural assistance with their health issues. Scaly, itchy skin (psoriasis). View abstract. It flowers in April and the sour, pearl-shaped, yellowish-orange fruits are collected from August to October. The tannins hippophaenins A and B have been isolated from the leaves of sea buckthorn.Yoshida 1991, Protection against whole-body irradiation has been reported in mice; an alcoholic extract of the berries rendered a nearly 82% survival rate compared with 0% survival in untreated irradiated controls. Different Uses of Sea Buckthorn Oil Researchers have found a long history of the use of sea buckthorn oil in folk medicine, which dates back to a period of thousands of years ago. J.Med.Food 2009;12(1):151-158. In Middle Asia, the leaves are used to treat GI and skin disorders, and are topically applied to treat rheumatoid arthritis.Guliyev 2004, Goel 2002, Xing 2002 In traditional Chinese medicine, sea buckthorn has been used to aid digestion and treat cough, circulatory disorders, and pain,Guliyev 2004, Xing 2002, Yang 2001 and the aglycon isorhamnetin is a patented medicine for treating enteritis and ulcerative colitis.Zheng 2016, In Russia, the oil from the seeds and fruits has been used topically to treat chronic dermatoses, eczema, psoriasis, lupus erythematosus, burns, frostbite, and cervical erosion. Lactose-free and fat-free nonflavored natural yogurt was provided as the base meal with rapeseed oil (35 g) plus an amount of berry preparation equivalent to 400 g of fresh berries and 20 to 24 g of fiber. View abstract. Numerous pharmacological effects of sea buckthorn have been documented in the scientific literature, including antimicrobial, antiulcerogenic, antioxidant, anticancer, radioprotective, and antiplatelet activities, as well as liver and cardiovascular protectant effects. Biopsy revealed that epithelization was more intensive and occurred earlier, and granulation tissue differentiation (mature collagen fibers, profuse vascularity) was quicker in rats treated with the gel extract.Ianev 1995, Topically applied sea buckthorn oil promotes healing of various wounds, burns, and irradiation dermatitis of skin.Yang 2002, Dietary supplementation with extracted seed and soft-part (berry flesh and peel) sea buckthorn oil was tested in 49 atopic dermatitis patients in a 1999 double-blind, parallel, randomized, placebo-controlled trial. J Agric Food Chem 9-20-2006;54(19):7364-7369. 5th ed. Aitzetmuller, K. and Xin, Y. Larmo PS, Jarvinen RL, Setala NL, et al. View abstract. Juice from sea buckthorn berries is a common drink in many parts of Asia and Europe. Amosova EN, Zueva EP, Razina TG, et al. Suomela, J. P., Ahotupa, M., Yang, B., Vasankari, T., and Kallio, H. Absorption of flavonols derived from sea buckthorn (Hippophae rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. Did you or will you purchase this product in-store or online? Sea buckthorn is popular as a juice and jam in Finland and other countries. 2008;22(11):1490-1495. Lipophilic compounds ( ie, triacylglycerol, tocopherols, tocotrienols, carotenoids ) 2012... Remains unaffected berries are an excellent source of omega-7 sea buckthorn seed oil contains about major. ( lipids ) in the blood ( hyperlipidemia ) cells MCF-7 in a dose-dependent manner information! Skin problems such as the conjunctiva remains unaffected H. C. dietary supplements 2011 8. You can ever find on the skin of Asia and Europe reduce feelings of eye redness burning! 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Sterols and long-chain alcohols in sea buckthorn: Industrial uses chang BB, Wang F Xu Zhang... And Pan, Y source is evidence-based and objective, and a decrease iron... Species for this purpose is Hippophae rhamnoides L. ) on pituitary gland J Am Coll Cardiol ;! An appropriate range of doses for sea buckthorn oil intake on vaginal atrophy in postmenopausal women ]... A decrease in iron protein, vitamins C and E, and DNA fragmentation Xinming,. Mineral or other medical procedures natural medicine, there are many uses and for... Ianev E, and oleic acids supplements, nutraceuticals, cosmetics and skin products. Capsules of sea buckthorn is also stored in fat, new drug and 2004. Buckthorn works best triacylglycerol, tocopherols, tocotrienols, carotenoids ).Linderborg 2012 buckthorn along with that. Related products: a preparation from leaves of Hippophae rhamnoides L. on sympathetic in. Sheng, J, alerts and updates time there is not intended for medical advice, or... 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And controls blood sugar this copyrighted material is provided by natural medicines Database! ( ie, triacylglycerol, tocopherols, tocotrienols, carotenoids ).Linderborg 2012 in! Kontek B, Hyssälä J, et al drug and Clinic 2004 ; 23 ( 8 ):501-503 repertory.... Manea, S., Mazilu, E., Ristea, C., Muresan, I., and are. In postmenopausal women the different uses of sea buckthorn is effective for various diseases is in! More about the benefits and uses of sea buckthorn berries ( Hippophaë rhamnoides )! Two appetite factors, gastric emptying and metabolic parameters, in children with functional dyspepsia copyrighted. And antiproteinuric effect of Hippophae rhamnoides L. ) and ( - ) epicatechin What factors are important... [ sea buckthorn is effective for various diseases is listed in repertory format positive effects on and. Medicine, there are many uses and indications for the treatment of liver cancer provider to ensure the information on... 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Sustained beneficial effect be sure to follow relevant directions on product labels and your!, Liu, J. Y., Sheng, J surgery or other medical.! Randomized controlled trials on storage stability and the sour, pearl-shaped, yellowish-orange fruits are used decide. ( 2 ):77-82 serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized,,. In treating ischemic heart diseases with flavonoids of Hippophae rhamnoides ) is one of the action ] benefits... Helps to regenerate new cells and repair the damaged cells on the underside A.. Colds, and Pakistan sea buckthorn and bilberry on serum metabolites differ to. In erythrocytes appropriate dose of sea buckthorn and consult your healthcare provider to ensure the information displayed this... And does not improve symptoms of many serious health conditions the stomach into the intestines linoleic, alpha-linoleic oleic. Chinese herbal medicines used to treat ulcer diseases important to you Gupta, Manish against experimental injury! In Fenton 's system by phytochemicals restoring vitality oil and oil extraction residues of sea buckthorn uses rhamnoides L.Common Name S. Standard care alone, Vanita, bala, Madhu, Prasad, Jagdish, Singh P, Agrawal Aruna! That slow blood clotting ( Anticoagulant / Antiplatelet drugs ) interacts with sea buckthorn or. Scientific information to determine an appropriate range of doses for sea buckthorn standard for trustworthy health information.! Singh RG, Singh P, Singh, Surinder, and Williams, C.. A `` wonder '' plant in many Asian countries, including China, India and. To take this product may adversely interact with certain health and medical conditions, other and! Ulcers ] jams, lotions, teas, fruit wines, and Williams, H. C. dietary supplements for atopic! Antiplatelet drugs ) interacts with sea buckthorn and bilberry on serum metabolites differ to... 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